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Drug Testing in the Workplace

Side Effects of Illegal Drug Abuse
(Your Brain on Drugs)

Below are the side effects and other information about the commonly-abused types of drugs known as the "SAMHSA Five." This information is courtesy of the U.S. Department of Justice, Drug Enforcement Administration (DEA).

Drugs of Abuse

Drug: Amphetamine Derivatives
Classification: Hallucinogen
CSA Schedule: Schedule I
Trade or Other Names: 2,5-DMA; STP; MDA; MDMA; Ecstasy; DOM; DOB
Medical Uses: None
Physical Dependence: Unknown
Psychological Dependence: Unknown
Tolerance: Yes
Duration (hours): Variable
Usual Method: Oral; Injected
Possible Effects: Illusions and hallucinations; Altered perception of time and distance
Effects of Overdose: Longer, more intense "trip" episodes; Psychosis; Possible death
Withdrawal Syndrome: Unknown
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Drug: Amphetamine/Methamphetamine
Classification: Stimulant
CSA Schedule: Schedule II
Trade or Other Names: Biphetamine; Desoxyn; Dexedrine; Obetrol; Ice
Medical Uses: Attention deficit disorder; Narcolepsy; Weight control
Physical Dependence: Possible
Psychological Dependence: High
Tolerance: Yes
Duration (hours): 2-4
Usual Method: Oral; Injected; Smoked
Possible Effects: Increased alertness; Excitation; Euphoria; Increased pulse rate & blood pressure; Insomnia; Loss of appetite
Effects of Overdose: Agitation; Increased body temperature; Hallucinations; Convulsions; Possible death
Withdrawal Syndrome: Apathy; Long periods of sleep; Irritability; Depression; Disorientation
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Drug: Cocaine
Classification: Stimulant
CSA Schedule: Schedule II
Trade or Other Names: Coke; Flake; Snow; Crack (Cocaine is designated a narcotic under the CSA)
Medical Uses: Local anesthetic
Physical Dependence: Possible
Psychological Dependence: High
Tolerance: Yes
Duration (hours): 1-2
Usual Method: Sniffed; Smoked; Injected
Possible Effects: Increased alertness; Excitation; Euphoria; Increased pulse rate & blood pressure; Insomnia; Loss of appetite
Effects of Overdose: Agitation; Increased body temperature; Hallucinations; Convulsions; Possible death
Withdrawal Syndrome: Apathy; Long periods of sleep; Irritability; Depression; Disorientation
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Drug: Codeine
Classification: Narcotic
CSA Schedule: Schedule II, III, V
Trade or Other Names: Tylenol w/Codeine; Empirin w/Codeine; Robitussin A-C; Fiorinal w/Codeine; APAP w/Codeine
Medical Uses: Analgesic; Antitussive
Physical Dependence: Moderate
Psychological Dependence: Moderate
Tolerance: Yes
Duration (hours): 3-6
Usual Method: Oral; Injected
Possible Effects: Euphoria; Drowsiness; Respiratory depression; Constricted pupils; Nausea
Effects of Overdose: Slow and shallow breathing; Clammy skin; Convulsions; Coma; Possible death
Withdrawal Syndrome: Watery eyes; Runny nose; Yawning; Loss of appetite; Irritability; Tremors; Panic; Cramps; Nausea; Chills & sweating
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Drug: Heroin
Classification: Narcotic
CSA Schedule: Schedule I
Trade or Other Names: Diacetylmorphine; Horse; Smack
Medical Uses: None in United States; Analgesic; Antitussive
Physical Dependence: High
Psychological Dependence: High
Tolerance: Yes
Duration (hours): 3-6
Usual Method: Injected; Sniffed; Smoked
Possible Effects: Euphoria; Drowsiness; Respiratory depression; Constricted pupils; Nausea
Effects of Overdose: Slow and shallow breathing; Clammy skin; Convulsions; Coma; Possible death
Withdrawal Syndrome: Watery eyes; Runny nose; Yawning; Loss of appetite; Irritability; Tremors; Panic; Cramps; Nausea; Chills & sweating
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Drug: Marijuana (Hashish/Hashish Oil)
Classification: Cannabis
CSA Schedule: Schedule I
Trade or Other Names: Pot; Acapulco Gold; Grass; Reefer; Sinsemilla; Thai sticks
Medical Uses: None
Physical Dependence: Unknown
Psychological Dependence: Moderate
Tolerance: Yes
Duration (hours): 2-4
Usual Method: Smoked; Oral
Possible Effects: Euphoria; Relaxed inhibitions; Increased appetite; Disorientation
Effects of Overdose: Fatigue; Paranoia; Possible psychosis
Withdrawal Syndrome: Occasional reports of insomnia; Hyperactivity; Decreased appetite
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Drug: Morphine
Classification: Narcotic
CSA Schedule: Schedule II
Trade or Other Names: Duramorph; MS-Contin; Roxanol; Oramorph SR
Medical Uses: Analgesic
Physical Dependence: High
Psychological Dependence: High
Tolerance: Yes
Duration (hours): 3-6
Usual Method: Oral; Smoked; Injected
Possible Effects: Euphoria; Drowsiness; Respiratory depression; Constricted pupils; Nausea
Effects of Overdose: Slow and shallow breathing; Clammy skin; Convulsions; Coma; Possible death
Withdrawal Syndrome: Watery eyes; Runny nose; Yawning; Loss of appetite; Irritability; Tremors; Panic; Cramps; Nausea; Chills & sweating
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Drug: Phencyclidine & Analogs
Classification: Hallucinogen
CSA Schedule: Schedule I, II
Trade or Other Names: PCE; PCPy; TCP; PCP; Hog; Loveboat; Angel Dust
Medical Uses: None
Physical Dependence: Unknown
Psychological Dependence: High
Tolerance: Yes
Duration (hours): Days
Usual Method: Oral; Smoked
Possible Effects: Illusions and hallucinations; Altered perception of time and distance
Effects of Overdose: Longer, more intense "trip" episodes; Psychosis; Possible death
Withdrawal Syndrome: Unknown
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Schedule I and II drugs have a high potential for abuse. They require greater storage security and have a quota on manufacture among other restrictions. Schedule I drugs are available for research only and have no approved medical use. Schedule II drugs are available only through prescription, cannot have refills and require a form for ordering. Schedule III and IV drugs are available with prescription, may have 5 refills in 6 months and may be ordered orally. Most Schedule V drugs are available over the counter.
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